Health itself is now a source of anxiety, “wellness” a pressing individual responsibility. That the built environment can make us sick has become clear. It’s tempting to believe that architecture or urban planning could also make us better—cure or soothe our bodies, help us get in shape, alleviate our stress. This issue explores these connections and interventions and the specific assumptions that nourish them. It registers real progress; it also considers the nauseating likelihood that our best intentions might only introduce new complications.